Unraveling the therapeutic efficacy of resveratrol in Alzheimer's disease: an umbrella review of systematic evidence.
Ali AzargoonjahromiFatemeh AbutalebianPublished in: Nutrition & metabolism (2024)
RV exhibits promising potential for benefiting individuals with AD through various mechanisms. It has been observed to enhance cognitive function, reduce Aβ accumulation, provide neuroprotection, protect the BBB, support mitochondrial function, facilitate synaptic plasticity, stabilize tau proteins, mitigate oxidative stress, and reduce neuroinflammation commonly associated with AD.
Keyphrases
- oxidative stress
- cerebral ischemia
- mycobacterium tuberculosis
- blood brain barrier
- traumatic brain injury
- cognitive decline
- brain injury
- dna damage
- lipopolysaccharide induced
- lps induced
- ischemia reperfusion injury
- cognitive impairment
- randomized controlled trial
- systematic review
- meta analyses
- subarachnoid hemorrhage
- induced apoptosis
- human health
- signaling pathway
- risk assessment
- mild cognitive impairment
- heat shock protein