Synergistic Chemopreventive Effects of a Novel Combined Plant Extract Comprising Gallic Acid and Hesperidin on Colorectal Cancer.

Szu-Jung ChenJui-Hua LuChih-Cheng LinShao-Wei ZengJia-Feng ChangYuan-Chiang ChungHsiang ChangChih-Ping Hsu

Published in: Current issues in molecular biology (2023)

Gallic acid and hesperidin exert synergistic effects on cell growth, spheroids, and stemness of CRC and may serve as a potential chemopreventive agent. Further testing for the safety and effectiveness of the combined extract in large-scale randomized trials is required.

Keyphrases

oxidative stress
stem cells
randomized controlled trial
cancer therapy
systematic review
anti inflammatory
epithelial mesenchymal transition
drug delivery