Protocol for the Wessex AsThma CoHort of difficult asthma (WATCH): a pragmatic real-life longitudinal study of difficult asthma in the clinic.

Adnan AzimHeena MistryAnna FreemanClair BarberColin NewellKerry GoveYvette ThirlwallMatt HarveyKimberley BentleyDeborah KnightKaren LongFrances MitchellYueqing ChengJudit Varkonyi-SeppWolfgang GrabauPaddy DennisonHans Michael HaitchiS Hasan ArshadRatko DjukanovicTom WilkinsonPeter HowarthRamesh J Kurukulaaratchy

Published in: BMC pulmonary medicine (2019)

The pragmatic ongoing nature of the WATCH study allows comprehensive assessment of the real world clinical spectrum seen in a Specialist Asthma Centre and allows a longitudinal perspective of deeply phenotyped patients. It is anticipated that the WATCH cohort would act as a vehicle for potential collaborative asthma studies and will build upon our understanding of mechanisms underlying difficult asthma.

Keyphrases

chronic obstructive pulmonary disease
lung function
allergic rhinitis
end stage renal disease
randomized controlled trial
primary care
ejection fraction
peritoneal dialysis
quality improvement