Early loss of T lymphocyte 4-1BB receptor expression is associated with higher short-term mortality in alcoholic hepatitis.

Lotte Lindgreen EriksenMorten Aagaard NielsenTea Lund LaursenBent DeleuranHendrik VilstrupSidsel Støy

Published in: PloS one (2021)

We found an increased stimulated 4-1BB response of T lymphocytes in AH and early loss of these lymphocytes was associated with a higher short-term mortality. This suggests a role of T lymphocyte 4-1BB expression in the progression of AH.

Keyphrases

growth factor
peripheral blood
cardiovascular events
recombinant human
poor prognosis
risk factors
type diabetes
cardiovascular disease
binding protein
long non coding rna