Transcriptomic analyses of lung tissues reveal key genes associated with progression of systemic sclerosis-interstitial lung disease (SSc-ILD).
Yehya Al-AdwiJohanna WestraHarry van GoorLeon C van KempenMohammed OsmanC Tji GanWim TimensDouwe J Mulder
Published in: Journal of autoimmunity (2024)
More cdkn2c and less peli1 expression were associated with more advanced stages of SSc-ILD on histologic assessment. We report the potential of the cell cycle inhibitor and senescence marker, cdkn2c (p18) to be associated with fibrosis progression.