Development of Core Outcome Measures sets for paediatric and adult Severe Asthma (COMSA).
Ekaterina KhalevaAnna RattuChris BrightlingAndrew BushApostolos BossiosArnaud BourdinKian Fan ChungRekha ChaudhuriCourtney ColemanSven-Erik DahlénRatko DjukanovicAntoine DeschildreLouise J FlemingStephen J FowlerAtul GuptaEckard HamelmannSimone HashimotoGunilla HedlinGerard H KoppelmannErik MelénClare S MurrayCharles PiletteCeleste PorsbjergKatharine C PikeFranca RusconiClare WilliamsBirgit AhrensPeter AlterFreja AnckersMaarten van den BergeKatharina BlumchenGuy BrusselleGraham W ClarkeDanen CunoosamyBarbro DahlénPiers DixeyAndrew ExleyUrs FreyErol A GaillardLisa Giovannini-ChamiJonathan GriggDiana HartensteinLiam G HeaneyBülent KaradagSusanne KaulInger KullAmelia LicariAnke H Maitland-van der ZeeVera MahlerAnn-Marie M SchoosPrasad NagakumarJenny NegusHanna NielsenJames PatonMariëlle PijnenburgValeria RamiconiSofia Romagosa VilarnauStefania PrincipeNiels RutjesSejal SaglaniPaul SeddonFlorian SingerHeribert StaudingerStephen W TurnerSusanne VijverbergTonya WindersValentyna YasinskaGraham C Robertsnull nullPublished in: The European respiratory journal (2022)
This patient-centred collaboration has produced two COM sets for paediatric and adult severe asthma. It is expected that they will inform the methodology of future clinical trials, enhance comparability of efficacy and effectiveness of biological therapies, and help assess their socioeconomic value. COMSA will inform definitions of non-response and response to biological therapy for severe asthma.