Antitumor Effect of miR-1294/Pyruvate Kinase M2 Signaling Cascade in Osteosarcoma Cells.

Quan YuanHonghao YuJianhua Chen Xiao-Yu SongLi Sun

Published in: OncoTargets and therapy (2020)

Our results revealed that miR-1294/PKM2 signaling cascade exerts important roles in the regulation of tumor progression, implying that this pathway may serve as a potential therapeutic target in osteosarcoma.

Keyphrases

cell proliferation
long non coding rna
long noncoding rna
induced apoptosis
poor prognosis
cell cycle arrest
single cell
tyrosine kinase
oxidative stress
protein kinase
climate change