Role of lncSLCO1C1 in gastric cancer progression and resistance to oxaliplatin therapy.

Yu-Feng XiaoBo-Sheng LiJing-Jing LiuSu-Min WangJiao LiuHuan YangYi-Yang HuChun-Li GongJi-Liang Li Shi-Ming Yang

Published in: Clinical and translational medicine (2022)

LncSLCO1C1 promotes GC progression by enhancing cell growth and preventing DNA damage via interacting and scaffolding the SSRP1/H2A/H2b complex and absorbing both miR-211-5p and miR-204-5p to increase SSRP1 expression.

Keyphrases

dna damage
poor prognosis
oxidative stress
dna repair
stem cells
protein kinase
mesenchymal stem cells
high resolution
cell therapy