Molecular profiling METex14+ non-small cell lung cancer (NSCLC): Impact of histology.

Jennifer A MarksNishant GandhiBalazs HalmosMelina E MarmarelisSo Yeon KimLyudmila BazhenovaSuresh S RamalingamJoanne XiuPhillip WalkerMatthew J OberleyPatrick C MaStephen V Liu

Published in: Lung cancer (Amsterdam, Netherlands) (2024)

METex14+ alterations are a heterogeneous subgroup of NSCLC. Our analysis reveals that METex14+ nSq exhibit improved survival compared to METex14+ Sq. The distinct genomic and transcriptomic variations across histologies warrant clinical consideration.

Keyphrases

small cell lung cancer
advanced non small cell lung cancer
single cell
brain metastases
randomized controlled trial
gene expression
clinical trial
single molecule
phase iii
open label
genome wide
double blind
placebo controlled