Using human iPS cell-derived enterocytes as novel in vitro model for the evaluation of human intestinal mucosal damage.

Satoshi KondoShota MizunoTadahiro HashitaTakahiro IwaoTamihide Matsunaga

Published in: Inflammation research : official journal of the European Histamine Research Society ... [et al.] (2018)

The developed model could facilitate evaluating drug-induced mucosal damage and protective effects of various agents and could impact drug development studies regarding pharmacological efficacy and safety.

Keyphrases

drug induced
endothelial cells
liver injury
oxidative stress
induced pluripotent stem cells
pluripotent stem cells
ulcerative colitis