L-carnitine contributes to enhancement of viability and quality of platelet concentrates through changing the apoptotic and anti-apoptotic associated microRNAs.

Mozhgan NorouziSeyed Alireza Mesbah-NaminZohreh SharifiMohammad Reza Deyhim

Published in: Transfusion clinique et biologique : journal de la Societe francaise de transfusion sanguine (2024)

LC has a protective effect on platelet apoptosis, reduces the expression of apoptotic microRNA, and prevents the reduction of anti-apoptotic microRNA.

Keyphrases

cell death
cell cycle arrest
anti inflammatory
poor prognosis
oxidative stress
endoplasmic reticulum stress
cell proliferation
binding protein
long non coding rna
liquid chromatography
solid phase extraction