Trending Topics on Coumarin and Its Derivatives in 2020.
Aitor CarneiroMaria João MatosEugenio UriarteLourdes SantanaPublished in: Molecules (Basel, Switzerland) (2021)
Coumarins are naturally occurring molecules with a versatile range of activities. Their structural and physicochemical characteristics make them a privileged scaffold in medicinal chemistry and chemical biology. Many research articles and reviews compile information on this important family of compounds. In this overview, the most recent research papers and reviews from 2020 are organized and analyzed, and a discussion on these data is included. Multiple electronic databases were scanned, including SciFinder, Mendeley, and PubMed, the latter being the main source of information. Particular attention was paid to the potential of coumarins as an important scaffold in drug design, as well as fluorescent probes for decaging of prodrugs, metal detection, and diagnostic purposes. Herein we do an analysis of the trending topics related to coumarin and its derivatives in the broad field of drug discovery.
Keyphrases
- drug discovery
- living cells
- fluorescent probe
- tissue engineering
- label free
- big data
- health information
- structure activity relationship
- working memory
- small molecule
- electronic health record
- quantum dots
- meta analyses
- real time pcr
- loop mediated isothermal amplification
- randomized controlled trial
- healthcare
- social media
- climate change
- artificial intelligence
- deep learning
- sensitive detection