Post-transplant-cyclophosphamide and short-term Everolimus as graft-versus-host-prophylaxis in patients with relapsed/refractory lymphoma and myeloma-Final results of the phase II OCTET-EVER trial.
Tim RichardsonChristof ScheidMarco HerlingLukas P FrenzelCarmen HerlingMarta Rebecca Cruz AguilarSebastian TheurichMichael HallekUdo HoltickPublished in: European journal of haematology (2024)
Using PTCy and short-term Everolimus is safe with low rates of aGvHD and no severe aGvHD or cGvHD translating into a low rate of non-relapse mortality. Our results in this difficult to treat patient population are encouraging and warrant further studies.
Keyphrases
- phase ii
- clinical trial
- open label
- phase iii
- diffuse large b cell lymphoma
- multiple myeloma
- acute lymphoblastic leukemia
- acute myeloid leukemia
- low dose
- study protocol
- high dose
- cardiovascular events
- double blind
- case report
- randomized controlled trial
- risk factors
- hodgkin lymphoma
- newly diagnosed
- free survival
- case control