Can quantitative MRI be used in the clinical setting to quantify the impact of intra-articular glucocorticoid injection on synovial disease activity in juvenile idiopathic arthritis?
Joshua L BennettAmanda WoodNicola SmithRavi MistryKaren AllenSharmila JandialJohn D TuckettS Claire GowdyHelen E FosterFlora McErlaneKieren G HollingsworthPublished in: Pediatric rheumatology online journal (2019)
IAGI led to a marked reduction in synovial volume, with quantitative MRI identifying more patients with an improved synovial volume than routine qualitative clinical reporting. Improvements in cJADAS scores were more variable with the patient/parent global assessment component contributing most to the scores. Further work is indicated, exploring the utility of quantitative MRI in the assessment of less accessible joints and comparing the impact of different treatment modalities.
Keyphrases
- juvenile idiopathic arthritis
- disease activity
- contrast enhanced
- rheumatoid arthritis
- systemic lupus erythematosus
- magnetic resonance imaging
- high resolution
- rheumatoid arthritis patients
- diffusion weighted imaging
- ankylosing spondylitis
- computed tomography
- systematic review
- magnetic resonance
- case report
- clinical practice
- ultrasound guided
- drug induced
- electronic health record