Activation of the Melanocortin-4 receptor signaling by α-MSH stimulates nerve-dependent mouse digit regeneration.

Hanqian XuHailin ZhangYanqing FangHuiran YangYing ChenChao ZhangGufa Lin

Published in: Cell regeneration (London, England) (2021)

Mc4r expression in the mouse limb and digit is closely related to nerve tissues, and α-MSH/MC4R signaling has a neurotrophic role in mouse digit tip regeneration.

Keyphrases

stem cells
poor prognosis
gene expression
peripheral nerve