Effects of Oleo Gum Resin of Ferula assa-foetida L. on Senescence in Human Dermal Fibroblasts: - Asafoetida reverses senescence in fibroblasts.

Farshad Homayouni MoghadamMehrnaz Mesbah-ArdakaniMohammad Hossein Nasr-Esfahani

Published in: Journal of pharmacopuncture (2017)

The results of this study indicate that asafetida at low concentrations has a rejuvenating effect on senescent fibroblasts whereas at higher concentrations, it has the opposite effect of facilitating cellular apoptosis and death.

Keyphrases

endothelial cells
extracellular matrix
dna damage
oxidative stress
stress induced
endoplasmic reticulum stress
cell death
induced pluripotent stem cells
cell cycle arrest
pluripotent stem cells
signaling pathway
wound healing