Login / Signup

Iodine/TBHP-Mediated One-Pot Multicomponent Protocol for Tandem C-N and C-S Bond Formation To Access Sulfenylimidazo[1,5- a ]pyridines via C-H Functionalization.

Shivangani MahajanSanghapal D Sawant
Published in: The Journal of organic chemistry (2022)
A mild and simple protocol has been established for the formation of sulfenylated imidazo[1,5- a ]pyridines. This is a metal-free iodine/TBHP-mediated one-pot multicomponent reaction, which follows C-H functionalization of the imidazo[1,5- a ]pyridine skeleton formed during the reaction and its subsequent sulfenylation in the same step to offer sulfenylated imidazo[1,5- a ]pyridines in good to high yields. The extension and applications of this method have also been demonstrated.
Keyphrases
  • randomized controlled trial
  • dual energy
  • electron transfer
  • magnetic resonance imaging
  • magnetic resonance
  • transition metal