Serum Small Extracellular Vesicles Proteome of Tuberculosis Patients Demonstrated Deregulated Immune Response.
Rakesh AryaDeepti DabralHossain Md FaruqueeHimangshu MazumdarSaurav Jyoti PatgiriTrinayan DekaRumi BasumataryRukuwe-U KupaChayale SemyWetetsho KapfoKevideme LiegiseInderjeet KaurTenzin ChoedonPurnima KumarRajendra Kumar BeheraPranjal DeoriReema NathKerekha KhaloLahari SaikiaVinotsole KhamoRanjan Kumar NandaPublished in: Proteomics. Clinical applications (2019)
These important proteins, involved in neutrophil degranulation, plasma heme scavenging, kynurenine, and lipid metabolism, show deregulation in ATB patients. Identification of such a protein panel in circulating small EVs besides providing novel insights into their role in tuberculosis may prove to be useful targets to develop host-directed therapeutic intervention.
Keyphrases