Immune-Checkpoint-Inhibitor-Related Lung Toxicity: A Multicentre Real-Life Retrospective Portrait from Six Italian Centres.

Paolo Cameli Paola FaverioKatia FerrariViola BontiStefania MarsiliMaria Antonietta MazzeiFrancesca MazzoniMaurizio BartolucciVieri ScottiFederica BertoliniFausto BarbieriCinzia Baldessari Chiara Veronese Roberto BoffiMatteo BrighentiDiego Luigi Cortinovis Massimo DominiciAlberto PesciElena BargagliFabrizio Luppi

Published in: Life (Basel, Switzerland) (2022)

Our cohort showed heterogeneous clinical and radiological aspects of ICI-related lung toxicity, with a latency not limited to the first year of treatment. Severity was mainly mild to moderate, although life-threatening events did occur. Our data indicate that strict long-term follow-up is needed to enable early diagnosis and appropriate management.

Keyphrases

oxidative stress
clinical trial
electronic health record
study protocol
randomized controlled trial
machine learning
big data
deep learning
artificial intelligence
double blind
combination therapy
drug induced