Switching from combination therapy with entecavir hydrate plus tenofovir alafenamide fumarate to tenofovir alafenamide fumarate monotherapy in patients with chronic hepatitis B based on nucleotide sequences of hepatitis B virus pregenome RNA.
Shunsuke YamadaYoshihito UchidaJun-Ichi KouyamaKayoko NaikiShohei TsujiHayato UemuraKayoko SugawaraNobuaki NakayamaYukinori ImaiTomoaki TomiyaSuguru MizunoSatoshi MochidaPublished in: Hepatology research : the official journal of the Japan Society of Hepatology (2024)
Patients receiving ETV plus TAF due to partial response or BTH during initial LAM or ETV administration were able to safely transition to TAF monotherapy based on nucleotide sequences of HBV pregenome RNA in the sera.