Eculizumab versus rituximab in generalised myasthenia gravis.
Christopher NelkeChristina B SchroeterFrauke StascheitMarc PawlitzkiLiesa Regner-NelkeNiklas HuntemannErcan AratMenekse ÖztürkNico MelzerPhilipp MergenthalerAsmae GassaHenning StetefeldMichael SchroeterBenjamin BergerAndreas TotzeckTim HagenackerStefanie SchreiberStefan VielhaberHans-Peter HartungAndreas MeiselHeinz WiendlSven G MeuthTobias RuckPublished in: Journal of neurology, neurosurgery, and psychiatry (2022)
This retrospective, observational study provides the first real-world evidence supporting the use of eculizumab for the treatment of refractory, anti-AChR-ab positive MG. Nonetheless, the risk of MC remained high and prompts the need for intensified monitoring and further research effort aimed at this vulnerable patient cohort.