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Trajectories of clinical characteristics, complications and treatment choices in data-driven subgroups of type 2 diabetes.

Xinyu LiLouise A DonnellyRoderick C SliekerJoline Wilhelma Johanna BeulensLeendert M 't HartPetra J M EldersEwan R PearsonAnoukh van GiessenShelby D ReedTalitha L Feenstra
Published in: Diabetologia (2024)
Data-driven subgroup allocations were generally consistent over follow-up and captured significant differences in risk factor trajectories, medication patterns and complication risks. Subgroups serve better as a complement rather than as a basis for compressing clustering indicators.
Keyphrases
  • type diabetes
  • risk factors
  • depressive symptoms
  • healthcare
  • single cell
  • cardiovascular disease
  • insulin resistance
  • human health
  • rna seq
  • randomized controlled trial
  • adverse drug
  • phase iii