Towards more accurate pharmacogenomic variant effect predictions.

Published in: Pharmacogenomics (2023)

Tweetable abstract Accurate variant interpretation has become a key bottleneck for the translation of an individual's pharmacogenome into actionable recommendations. We recommend an integrated use of multiplexed assays, structure-based predictions and biobank data to develop more accurate effect predictors.

Keyphrases

high resolution
high throughput
electronic health record
machine learning
mass spectrometry
clinical practice
deep learning