A thymic stromal lymphopoietin polymorphism may provide protection from asthma by altering gene expression.

Amy MooreheadRaphael HannaDelia HerouxHelen NeighbourAndrew SandfordGail M GauvreauDoron D SommerJudah A DenburgLoubna Akhabir

Published in: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology (2020)

The key finding on the influence of TSLP genetic variation on disease expression/endotype could provide basis for investigation into targeted biologics for anti-TSLP therapies.

Keyphrases

gene expression
poor prognosis
chronic obstructive pulmonary disease
dna methylation
bone marrow
lung function
cancer therapy
cystic fibrosis
drug delivery