Effectiveness of a Second Biologic After Failure of a Non-tumor Necrosis Factor Inhibitor As First Biologic in Rheumatoid Arthritis.
Katerina ChatzidionysiouMerete Lund HetlandThomas FrisellDaniela Di GiuseppeKarin HellgrenBente GlintborgDan NordströmRitva PeltomaaKalle AaltonenNina TrokovicEirik K KristianslundTore K KvienSella A ProvanBjorn GudbjornssonGerdur GrondalLene DreyerLars Erik KristensenTanja Schjødt JørgensenLennart T H JacobssonJohan AsklingPublished in: The Journal of rheumatology (2021)
The drug survival and primary response of a second bDMARD in patients with RA switching due to failure of a non-TNFi bDMARD as first bDMARD is modest. Some patients may benefit from TNFi when used after failure of a non-TNFi as first bDMARD.