The Efficacy of Immune Checkpoint Inhibitors vs. Chemotherapy for KRAS-Mutant or EGFR-Mutant Non-Small-Cell Lung Cancers: A Meta-Analysis Based on Randomized Controlled Trials.
Wei ChenLing LiSheng ChengJunxian YuPublished in: Disease markers (2022)
This research revealed that individuals with EGFR wild-type NSCLC or KRAS mutation may benefit from PD-L1/PD-1 inhibitors and that PD-L1/PD-1 inhibitors in combination with chemotherapy seem to be more successful than chemotherapy alone in NSCLC patients with EGFR mutation.
Keyphrases
- wild type
- small cell lung cancer
- epidermal growth factor receptor
- locally advanced
- tyrosine kinase
- advanced non small cell lung cancer
- single cell
- brain metastases
- randomized controlled trial
- cell therapy
- chemotherapy induced
- stem cells
- rectal cancer
- clinical trial
- systematic review
- radiation therapy
- mesenchymal stem cells