Interaction of KLAKLAK-NH 2 and Analogs with Biomimetic Membrane Models.

Victoria VitkovaKrassimira AntonovaOgnyan PetkovAngelina Stoyanova-Ivanova Sirine Jaber Vladislava Ivanova Emilia Naydenova Dancho L Danalev

Published in: Pharmaceutics (2024)

The reported results are expected to advance the progress in tailoring the pharmacokinetic properties of antimicrobial peptides with strengthened stability towards enzymatic degradation. The investigation of the nonspecific interactions of peptides with model lipid membranes is featured as a useful tool to assess the antitumor and antimicrobial potential of new peptide mimetics.

Keyphrases

staphylococcus aureus
hydrogen peroxide
molecular docking
room temperature
fatty acid
human health
amino acid
nitric oxide
climate change
ionic liquid