Pharmacogenetics of tuberculosis treatment toxicity and effectiveness in a large Brazilian cohort.

Gustavo AmorimJames JaworskiMarcelo Cordeiro-SantosAfrânio L KritskiMarina C FigueiredoMegan TurnerBruno Bezerril AndradeDigna R Velez EdwardsAdalberto R SantosValeria C RollaTimothy R SterlingDavid W Haasnull null

Published in: medRxiv : the preprint server for health sciences (2023)

acetylator status was associated with risk for treatment-related adverse events. Additional significant polymorphisms merit investigation in larger study populations.

Keyphrases

randomized controlled trial
mycobacterium tuberculosis
systematic review
oxidative stress
emergency department
replacement therapy
pulmonary tuberculosis