The immune microenvironment and expression of PD-L1, PD-1, PRAME and MHC I in salivary duct carcinoma.
Ronald A GhosseinAchim A JungbluthDenise FrosinaBayan AlzumailiNathaniel AleynickElzbieta SlodkowskaKevin HigginsAlan HoLuc MorrisRonald GhosseinNora KatabiPublished in: Histopathology (2019)
Alterations of the tumour immune microenvironment are common in SDCs, including expression of PD-1/PD-L1 and PRAME, which opens the way to potential novel immune therapies, such as cancer vaccination and PD-1/PD-L1 blockade, in these tumours.