Infections in baricitinib clinical trials for patients with active rheumatoid arthritis.

Kevin L Winthrop Masayoshi Harigai Mark C GenoveseStephen LindseyTsutomu TakeuchiRoy M FleischmannJohn D BradleyNicole L ByersDavid L HyslopMaher IssaAtsushi NishikawaTerence P RooneySarah WittChristina L DicksonJosef S SmolenMaxime Dougados

Published in: Annals of the rheumatic diseases (2020)

Increased rates of treatment-emergent infections including HZ were observed in patients with RA treated with baricitinib, consistent with baricitinib's immunomodulatory mode of action.

Keyphrases

rheumatoid arthritis
clinical trial
disease activity
ankylosing spondylitis
interstitial lung disease
randomized controlled trial
systemic sclerosis
open label
study protocol