Efficacy, acceptability and tolerability of second-generation antipsychotics for behavioural and psychological symptoms of dementia: a systematic review and network meta-analysis.

Wenqi LüFangzhou LiuYuwei ZhangXiance HeYongbo HuHuifang XuXin YangJin LiWeihong Kuang

Published in: BMJ mental health (2024)

Brexpiprazole showing great efficacy in the treatment of BPSD, with aripiprazole showing the highest acceptability and olanzapine showing the worst tolerability. The results of this study may be used to guide decision-making.

Keyphrases

decision making
open label
mild cognitive impairment
major depressive disorder
sleep quality
double blind
cognitive impairment
randomized controlled trial
clinical trial
physical activity
combination therapy