Estimating optimal therapeutic drug levels of anti-tuberculosis medications based on treatment safety and effectiveness.

Gustavo AmorimDavid W HaasMarcelo Cordeiro-SantosAfrânio L KritskiMarina C FigueiredoCody StaatsBrian HacheyMegan TurnerBruno Bezerril AndradeValeria C RollaTimothy R Sterlingnull null

Published in: medRxiv : the preprint server for health sciences (2024)

Our estimated upper end TDR were higher for INH and lower for RIF compared to currently recommended ranges.

Keyphrases

pulmonary tuberculosis
randomized controlled trial
mycobacterium tuberculosis
systematic review
adverse drug
hiv aids
emergency department
combination therapy
drug induced