Glyoxal-derived advanced glycation end-products, N ε -carboxymethyl-lysine, and glyoxal-derived lysine dimer induce apoptosis-related gene expression in hepatocytes.

Jison KangYu-Jin JeongSang Keun HaHyun Hee LeeKwang-Won Lee

Published in: Molecular biology reports (2023)

These findings suggest that AGE5 treatment activates the apoptosis-related gene expression in hapatocytes, with CML and GOLD as potential major AGE compounds.

Keyphrases

gene expression
oxidative stress
endoplasmic reticulum stress
dna methylation
cell cycle arrest
cell death
amino acid
risk assessment
human health
combination therapy
signaling pathway
climate change
pi k akt