Characterization of the dual functional effects of heat shock proteins (HSPs) in cancer hallmarks to aid development of HSP inhibitors.

Zhao ZhangJi JingYouqiong YeZhiao ChenYing JingShengli LiWei HongHang RuanYaoming LiuQingsong HuJun WangWenbo LiChunru LinLixia DiaoYubin ZhouLeng Han

Published in: Genome medicine (2020)

Our study furnishes a holistic view of functional associations of HSPs with cancer hallmarks to aid the development of HSP inhibitors as well as other drugs in cancer therapy.

Keyphrases

heat shock
heat shock protein
heat stress
papillary thyroid
cancer therapy
squamous cell
oxidative stress
drug delivery
squamous cell carcinoma
lymph node metastasis
young adults