Leng Han

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 74

Top Venues

Nature communications

Cancer research

Science advances

Genome medicine

University of Texas Health Science Center at Houston

Chinese Academy of Sciences (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Texas Health Science Center at Houston

United States

Assistant Professor

University of Texas MD Anderson Cancer Center

United States

Postdoc

Stanford University

United States

Postdoc

Education History

Chinese Academy of Sciences

China

PHD

Wuhan University

China

BSC

Publications

Zhenzhen Xun, Huanran Zhou, Mingyi Shen, Yao Liu, Chengcao Sun, Yanhua Du, Zhou Jiang, Liuqing Yang, Qing Zhang, Chunru Lin, Qingsong Hu, Youqiong Ye, Leng Han
Identification of Hypoxia-ALCAM high Macrophage- Exhausted T Cell Axis in Tumor Microenvironment Remodeling for Immunotherapy Resistance. Advanced science (Weinheim, Baden-Wurttemberg, Germany) (2024)
Lei Guo, Tingting Hong, Yi-Tsang Lee, Xue Hu, Guokai Pan, Rongjie Zhao, Yuhan Yang, Jingwen Yang, Xiaoli Cai, Logan Rivera, Jie Liang, Rui Wang, Yaling Dou, Srikanth Kodali, Wenbo Li, Leng Han, Bruno Di Stefano, Yubin Zhou, Jia Li, Yun Huang
Perturbing TET2 condensation promotes aberrant genome-wide DNA methylation and curtails leukaemia cell growth. Nature cell biology (2024)
Cheng-Cao Sun, Youqiong Ye, Zhi Tan, Yuan Liu, Yajuan Li, Wei Hu, Ke Liang, Sergey D Egranov, Lisa Angela Huang, Zhao Zhang, Yaohua Zhang, Yao Jun, Tina K Nguyen, Zilong Zhao, Andrew Wu, Jeffrey R Marks, Abigail S Caudle, Aysegul A Sahin, Jianjun Gao, Seth T Gammon, David Piwnica-Worms, Jian Hu, Paul J Chiao, Dihua Yu, Mien-Chie Hung, Michael A Curran, George A Calin, Haoqiang Ying, Leng Han, Chunru Lin, Liuqing Yang
Tumor-associated nonmyelinating Schwann cell-expressed PVT1 promotes pancreatic cancer kynurenine pathway and tumor immune exclusion. Science advances 9 (5) (2023)
Zhenzhen Xun, Xinyu Ding, Yao Zhang, Benyan Zhang, Shujing Lai, Duowu Zou, Junke Zheng, Guo-Qiang Chen, Bing Su, Leng Han, Youqiong Ye
Reconstruction of the tumor spatial microenvironment along the malignant-boundary-nonmalignant axis. Nature communications 14 (1) (2023)
Yu Dong, Qian Gao, Yong Chen, Zhao Zhang, Yanhua Du, Yuan Liu, Guangxiong Zhang, Shengli Li, Gaoyang Wang, Xiang Chen, Hong Liu, Leng Han, Youqiong Ye
Identification of CircRNA signature associated with tumor immune infiltration to predict therapeutic efficacy of immunotherapy. Nature communications 14 (1) (2023)
Cheng-Cao Sun, Youqiong Ye, Zhi Tan, Yuan Liu, Yajuan Li, Wei Hu, Ke Liang, Sergey D Egranov, Lisa Angela Huang, Zhao Zhang, Yaohua Zhang, Yao Jun, Tina K Nguyen, Zilong Zhao, Andrew Wu, Jeffrey R Marks, Abigail S Caudle, Aysegul A Sahin, Jianjun Gao, Seth T Gammon, David Piwnica-Worms, Jian Hu, Paul J Chiao, Dihua Yu, Mien-Chie Hung, Michael A Curran, George A Calin, Haoqiang Ying, Leng Han, Chunru Lin, Liuqing Yang
Tumor-associated nonmyelinating Schwann cell-expressed PVT1 promotes pancreatic cancer kynurenine pathway and tumor immune exclusion. Science advances 9 (5) (2023)
Yu Dong, Qian Gao, Yong Chen, Zhao Zhang, Yanhua Du, Yuan Liu, Guangxiong Zhang, Shengli Li, Gaoyang Wang, Xiang Chen, Hong Liu, Leng Han, Youqiong Ye
Identification of CircRNA signature associated with tumor immune infiltration to predict therapeutic efficacy of immunotherapy. Nature communications 14 (1) (2023)
Cheng-Cao Sun, Youqiong Ye, Zhi Tan, Yuan Liu, Yajuan Li, Wei Hu, Ke Liang, Sergey D Egranov, Lisa Angela Huang, Zhao Zhang, Yaohua Zhang, Yao Jun, Tina K Nguyen, Zilong Zhao, Andrew Wu, Jeffrey R Marks, Abigail S Caudle, Aysegul A Sahin, Jianjun Gao, Seth T Gammon, David Piwnica-Worms, Jian Hu, Paul J Chiao, Dihua Yu, Mien-Chie Hung, Michael A Curran, George A Calin, Haoqiang Ying, Leng Han, Chunru Lin, Liuqing Yang
Tumor-associated nonmyelinating Schwann cell-expressed PVT1 promotes pancreatic cancer kynurenine pathway and tumor immune exclusion. Science advances 9 (5) (2023)
Jingwen Yang, Yamei Chen, Ying Jing, Michael R Green, Leng Han
Advancing CAR T cell therapy through the use of multidimensional omics data. Nature reviews. Clinical oncology (2023)
Jingwen Yang, Yamei Chen, Ying Jing, Michael R Green, Leng Han
Advancing CAR T cell therapy through the use of multidimensional omics data. Nature reviews. Clinical oncology 20 (4) (2023)
Cheng-Cao Sun, Youqiong Ye, Zhi Tan, Yuan Liu, Yajuan Li, Wei Hu, Ke Liang, Sergey D Egranov, Lisa Angela Huang, Zhao Zhang, Yaohua Zhang, Yao Jun, Tina K Nguyen, Zilong Zhao, Andrew Wu, Jeffrey R Marks, Abigail S Caudle, Aysegul A Sahin, Jianjun Gao, Seth T Gammon, David Piwnica-Worms, Jian Hu, Paul J Chiao, Dihua Yu, Mien-Chie Hung, Michael A Curran, George A Calin, Haoqiang Ying, Leng Han, Chunru Lin, Liuqing Yang
Tumor-associated nonmyelinating Schwann cell-expressed PVT1 promotes pancreatic cancer kynurenine pathway and tumor immune exclusion. Science advances 9 (5) (2023)
Jingwen Yang, Yamei Chen, Ying Jing, Michael R Green, Leng Han
Advancing CAR T cell therapy through the use of multidimensional omics data. Nature reviews. Clinical oncology (2023)
Chengxuan Chen, Yuan Liu, Mei Luo, Jingwen Yang, Yamei Chen, Runhao Wang, Joseph Zhou, Yong Zang, Lixia Diao, Leng Han
PancanQTLv2.0: a comprehensive resource for expression quantitative trait loci across human cancers. Nucleic acids research (2023)
Yu Dong, Qian Gao, Yong Chen, Zhao Zhang, Yanhua Du, Yuan Liu, Guangxiong Zhang, Shengli Li, Gaoyang Wang, Xiang Chen, Hong Liu, Leng Han, Youqiong Ye
Identification of CircRNA signature associated with tumor immune infiltration to predict therapeutic efficacy of immunotherapy. Nature communications 14 (1) (2023)
Yuan Liu, Jingwen Yang, Tianlu Wang, Mei Luo, Yamei Chen, Chengxuan Chen, Ze'ev A Ronai, Yubin Zhou, Eytan Ruppin, Leng Han
Expanding PROTACtable genome universe of E3 ligases. Nature communications 14 (1) (2023)
Zhenzhen Xun, Xinyu Ding, Yao Zhang, Benyan Zhang, Shujing Lai, Duowu Zou, Junke Zheng, Guo-Qiang Chen, Bing Su, Leng Han, Youqiong Ye
Reconstruction of the tumor spatial microenvironment along the malignant-boundary-nonmalignant axis. Nature communications 14 (1) (2023)
Cheng-Cao Sun, Youqiong Ye, Zhi Tan, Yuan Liu, Yajuan Li, Wei Hu, Ke Liang, Sergey D Egranov, Lisa Angela Huang, Zhao Zhang, Yaohua Zhang, Yao Jun, Tina K Nguyen, Zilong Zhao, Andrew Wu, Jeffrey R Marks, Abigail S Caudle, Aysegul A Sahin, Jianjun Gao, Seth T Gammon, David Piwnica-Worms, Jian Hu, Paul J Chiao, Dihua Yu, Mien-Chie Hung, Michael A Curran, George A Calin, Haoqiang Ying, Leng Han, Chunru Lin, Liuqing Yang
Tumor-associated nonmyelinating Schwann cell-expressed PVT1 promotes pancreatic cancer kynurenine pathway and tumor immune exclusion. Science advances 9 (5) (2023)
Yu Dong, Qian Gao, Yong Chen, Zhao Zhang, Yanhua Du, Yuan Liu, Guangxiong Zhang, Shengli Li, Gaoyang Wang, Xiang Chen, Hong Liu, Leng Han, Youqiong Ye
Identification of CircRNA signature associated with tumor immune infiltration to predict therapeutic efficacy of immunotherapy. Nature communications 14 (1) (2023)
Jingwen Yang, Yamei Chen, Leng Han
A multi-omics perspective of CAR T cell therapy. Clinical and translational medicine 13 (5) (2023)
Zhenzhen Xun, Xinyu Ding, Yao Zhang, Benyan Zhang, Shujing Lai, Duowu Zou, Junke Zheng, Guo-Qiang Chen, Bing Su, Leng Han, Youqiong Ye
Reconstruction of the tumor spatial microenvironment along the malignant-boundary-nonmalignant axis. Nature communications 14 (1) (2023)
Chengxuan Chen, Yuan Liu, Qiang Li, Zhao Zhang, Mei Luo, Yaoming Liu, Leng Han
The genetic, pharmacogenomic, and immune landscapes associated with protein expression across human cancers. Cancer research (2023)
Zhenzhen Xun, Xinyu Ding, Yao Zhang, Benyan Zhang, Shujing Lai, Duowu Zou, Junke Zheng, Guo-Qiang Chen, Bing Su, Leng Han, Youqiong Ye
Reconstruction of the tumor spatial microenvironment along the malignant-boundary-nonmalignant axis. Nature communications 14 (1) (2023)
Yuan Yuan, Young Seok Ju, Young-Wook Kim, Jun Li, Yumeng Wang, Christopher J Yoon, Yang Yang, Inigo Martincorena, Chad J Creighton, John N Weinstein, Yanxun Xu, Leng Han, Hyung-Lae Kim, Hidewaki Nakagawa, Keunchil Park, Peter J Campbell, Han Liang, null null
Author Correction: Comprehensive molecular characterization of mitochondrial genomes in human cancers. Nature genetics (2023)
Mei Luo, Leng Han
Autophagy induction sensitizes cancer cells to anti-cancer drugs. Autophagy (2022)
Ying Jing, Jingwen Yang, Douglas B Johnson, Javid J Moslehi, Leng Han
Harnessing big data to characterize immune-related adverse events. Nature reviews. Clinical oncology 19 (4) (2022)
Zhen Liu, Youqiong Ye, Yizhe Liu, Yanfang Liu, Huifang Chen, Mengting Shen, Zhen Wang, Shenglin Huang, Leng Han, Xianghuo He, Xiang-Huo He
RNA Helicase DHX37 Facilitates Liver Cancer Progression by Cooperating with PLRG1 to Drive Superenhancer-Mediated Transcription of Cyclin D1. Cancer research 82 (10) (2022)
Marzia Savini, Andrew Folick, Yi-Tang Lee, Feng Jin, André Cuevas, Matthew C Tillman, Jonathon D Duffy, Qian Zhao, Isaiah A Neve, Pei-Wen Hu, Yong Yu, Qinghao Zhang, Youqiong Ye, William B Mair, Jin Wang, Leng Han, Eric A Ortlund, Meng C Wang
Lysosome lipid signalling from the periphery to neurons regulates longevity. Nature cell biology 24 (6) (2022)
Ying Jing, Yong-Chang Zhang, Jing Wang, Kunyan Li, Xue Chen, Jianfu Heng, Qian Gao, Youqiong Ye, Zhao Zhang, Yaoming Liu, Yanyan Lou, Steven Hsesheng Lin, Lixia Diao, Hong Liu, Xiang Chen, Gordon B Mills, Leng Han
Association Between Sex and Immune-Related Adverse Events During Immune Checkpoint Inhibitor Therapy. Journal of the National Cancer Institute 113 (10) (2022)
Xiao Zhou, Xiang Chen, Leng Han, Hong Liu
Mechanisms underlying immune-related adverse events during checkpoint immunotherapy. Clinical science (London, England : 1979) 136 (10) (2022)
Yaohua Zhang, Cheng-Cao Sun, Yajuan Li, Juan Qin, Kaushik Amancherla, Ying Jing, Qingsong Hu, Ke Liang, Zhao Zhang, Youqiong Ye, Lisa A Huang, Tina K Nguyen, Sergey D Egranov, Zilong Zhao, Andrew Wu, Yutao Xi, Yao Jun, Mien-Chie Hung, George A Calin, Jie Cheng, Bora Lim, Lorenz H Lehmann, Joe-Elie Salem, Douglas B Johnson, Michael A Curran, Dihua Yu, Leng Han, Radbod Darabi, Liuqing Yang, Javid J Moslehi, Chunru Lin
Hormonal therapies up-regulate MANF and overcome female susceptibility to immune checkpoint inhibitor myocarditis. Science translational medicine 14 (669) (2022)
Mei Luo, Leng Han
Autophagy induction sensitizes cancer cells to anti-cancer drugs. Autophagy (2022)
Zhao Zhang, Mei Luo, Qiang Li, Yuan Liu, Charles Lussier, Jian Zhang, Youqiong Ye, An-Yuan Guo, Leng Han
Genetic, Pharmacogenomic, and Immune Landscapes of Enhancer RNAs Across Human Cancers. Cancer research 82 (5) (2022)
Gaoyang Wang, Zuozhong Xie, Juan Su, Meishan Chen, Yanhua Du, Qian Gao, Guangxiong Zhang, Hailun Zhang, Xiang Chen, Hong Liu, Leng Han, Youqiong Ye
Characterization of Immune-Related Alternative Polyadenylation Events in Cancer Immunotherapy. Cancer research 82 (19) (2022)
Yuan Liu, Leng Han
TRUST4 Interrogates the Immune Receptor Repertoire in Oncology and Immunotherapy. Cancer immunology research 10 (7) (2022)
Mengting Shen, Shengli Li, Yiming Zhao, Yizhe Liu, Zhen Liu, Lin Huan, Yejun Qiao, Lu Wang, Leng Han, Xianghuo He, Xiang-Huo He
Hepatic ARID3A facilitates liver cancer malignancy by cooperating with CEP131 to regulate an embryonic stem cell-like gene signature. Cell death & disease 13 (8) (2022)
Mei Luo, Lin Ye, Ruimin Chang, Youqiong Ye, Zhao Zhang, Chun-Jie Liu, Shengli Li, Ying Jing, Hang Ruan, Guanxiong Zhang, Yi He, Yaoming Liu, Yu Xue, Xiang Chen, An-Yuan Guo, Hong Liu, Leng Han
Multi-omics characterization of autophagy-related molecular features for therapeutic targeting of autophagy. Nature communications 13 (1) (2022)
Ying Jing, Xue Chen, Kunyan Li, Yaoming Liu, Zhao Zhang, Yiqing Chen, Yuan Liu, Yushu Wang, Steven Hsesheng Lin, Lixia Diao, Jing Wang, Yanyan Lou, Douglas B Johnson, Xiang Chen, Hong Liu, Leng Han
Association of antibiotic treatment with immune-related adverse events in patients with cancer receiving immunotherapy. Journal for immunotherapy of cancer 10 (1) (2022)
Hang Ruan, Peng-Cheng Wang, Leng Han
Characterization of circular RNAs with advanced sequencing technologies in human complex diseases. Wiley interdisciplinary reviews. RNA (2022)
Jingjing Qi, Hongxiang Sun, Yao Zhang, Zhengting Wang, Zhenzhen Xun, Ziyi Li, Xinyu Ding, Rujuan Bao, Liwen Hong, Wenqing Jia, Fei Fang, Hongzhi Liu, Lei Chen, Jie Zhong, Duowu Zou, Lian-Xin Liu, Leng Han, Florent Ginhoux, Yingbin Liu, Youqiong Ye, Bing Su
Single-cell and spatial analysis reveal interaction of FAP + fibroblasts and SPP1 + macrophages in colorectal cancer. Nature communications 13 (1) (2022)
Liang Yan, Bo Tu, Yao Jun, Jing Gong, Alessandro Carugo, Christopher A Bristow, Qiuyun Wang, Cihui Zhu, Bingbing Dai, Ya'an Kang, Leng Han, Ningping Feng, Yanqing Jin, Jason Fleming, Timothy P Heffernan, Wantong Yao, Haoqiang Ying
Targeting Glucose Metabolism Sensitizes Pancreatic Cancer to MEK Inhibition. Cancer research 81 (15) (2021)
Zhao Zhang, Leng Han
Circular RNAs sequenced at last. Nature biotechnology 39 (7) (2021)
Zhao Zhang, Jian Zhang, Lixia Diao, Leng Han
Small non-coding RNAs in human cancer: function, clinical utility, and characterization. Oncogene 40 (9) (2021)
Jing Feng, Wenbo Chen, Xin Dong, Jun Wang, Xiangfei Mei, Jin Deng, Siqi Yang, Chenjian Zhuo, Xiaoyu Huang, Lin Shao, Rongyu Zhang, Jing Guo, Ronghui Ma, Juan Liu, Feng Li, Ying Wu, Leng Han, Chunjiang He
CSCD2: an integrated interactional database of cancer-specific circular RNAs. Nucleic acids research (2021)
Stephanie M Correa, Leng Han
Career pathways, part 4. Nature metabolism 3 (4) (2021)
Hang Ruan, Qiang Li, Yuan Liu, Yaoming Liu, Charles Lussier, Lixia Diao, Leng Han
GPEdit: the genetic and pharmacogenomic landscape of A-to-I RNA editing in cancers. Nucleic acids research (2021)
Yajuan Li, Zhi Tan, Yaohua Zhang, Zhao Zhang, Qingsong Hu, Ke Liang, Yao Jun, Youqiong Ye, Yi-Chuan Li, Chunlai Li, Lan Liao, Jianming Xu, Zhen Xing, Yinghong Pan, Sujash S Chatterjee, Tina K Nguyen, Heidi Hsiao, Sergey D Egranov, Nagireddy Putluri, Cristian Coarfa, David H Hawke, Preethi H Gunaratne, Kuang-Lei Tsai, Leng Han, Mien-Chie Hung, George A Calin, Fares Namour, Jean-Louis Guéant, Ania Carolina Muntau, Nenad Blau, Vernon Reid Sutton, Manuel Schiff, François Feillet, Shuxing Zhang, Chunru Lin, Liuqing Yang
A noncoding RNA modulator potentiates phenylalanine metabolism in mice. Science (New York, N.Y.) 373 (6555) (2021)
Yin Wang, Fang Yao, Lipeng Wang, Zheng Li, Zongna Ren, Dandan Li, Mingzhi Zhang, Leng Han, Shi-Qiang Wang, Bingying Zhou, Li Wang
Single-cell analysis of murine fibroblasts identifies neonatal to adult switching that regulates cardiomyocyte maturation. Nature communications 11 (1) (2020)
Yuan Yuan, Young Seok Ju, Young-Wook Kim, Jun Li, Yumeng Wang, Christopher J Yoon, Yang Yang, Inigo Martincorena, Chad J Creighton, John N Weinstein, Yanxun Xu, Leng Han, Hyung-Lae Kim, Hidewaki Nakagawa, Keunchil Park, Peter J Campbell, Han Liang, null null
Publisher Correction: Comprehensive molecular characterization of mitochondrial genomes in human cancers. Nature genetics (2020)
Tianhe Huang, Xi Cheng, Jad Chahoud, Ahmed Sarhan, Pheroze Tamboli, Priya Rao, Ming Guo, Ganiraju C Manyam, Li Zhang, Yu Xiang, Leng Han, Xiaoying Shang, Pingna Deng, Yanting Luo, Xuemin Lu, Shan Feng, Magaly Martinez Ferrer, Y Alan Wang, Ronald A DePinho, Curtis A Pettaway, Xin Lu
Effective combinatorial immunotherapy for penile squamous cell carcinoma. Nature communications 11 (1) (2020)
Li Wang, Peng Yu, Bingying Zhou, Jiangping Song, Zheng Li, Mingzhi Zhang, Guangran Guo, Yin Wang, Xiao Chen, Leng Han, Shengshou Hu
Single-cell reconstruction of the adult human heart during heart failure and recovery reveals the cellular landscape underlying cardiac function. Nature cell biology 22 (1) (2020)
Isaiah A A Neve, Jessica N Sowa, Chih-Chun J Lin, Priya Sivaramakrishnan, Christophe Herman, Youqiong Ye, Leng Han, Meng C Wang
Escherichia coli Metabolite Profiling Leads to the Development of an RNA Interference Strain for Caenorhabditis elegans. G3 (Bethesda, Md.) 10 (1) (2020)
Yaoming Liu, Hang Ruan, Shengli Li, Youqiong Ye, Wei Hong, Jing Gong, Zhao Zhang, Ying Jing, Xiulan Zhang, Lixia Diao, Leng Han
The genetic and pharmacogenomic landscape of snoRNAs in human cancer. Molecular cancer 19 (1) (2020)
Yaohua Zhang, Yajuan Li, Qingsong Hu, Yutao Xi, Zhen Xing, Zhao Zhang, Lisa Huang, Jianbo Wu, Ke Liang, Tina K Nguyen, Sergey D Egranov, Chengcao Sun, Zilong Zhao, David H Hawke, Jin Li, Deqiang Sun, Jean J Kim, Ping Zhang, Jie Cheng, Abid Farida, Mien-Chie Hung, Leng Han, Radbod Darabi, Chunru Lin, Liuqing Yang
The lncRNA H19 alleviates muscular dystrophy by stabilizing dystrophin. Nature cell biology 22 (11) (2020)
Youqiong Ye, Xinwei Kuang, Zuozhong Xie, Long Liang, Zhao Zhang, Yongchang Zhang, Fangyu Ma, Qian Gao, Ruimin Chang, Heng-Huan Lee, Shuang Zhao, Juan Su, Hui Li, Jingbo Peng, Huifang Chen, Minzhu Yin, Cong Peng, Nong Yang, Jing Wang, Jing Liu, Hong Liu, Leng Han, Xiang Chen
Small-molecule MMP2/MMP9 inhibitor SB-3CT modulates tumor immune surveillance by regulating PD-L1. Genome medicine 12 (1) (2020)
Yuan Yuan, Young Seok Ju, Young-Wook Kim, Jun Li, Yumeng Wang, Christopher J Yoon, Yang Yang, Inigo Martincorena, Chad J Creighton, John N Weinstein, Yanxun Xu, Leng Han, Hyung-Lae Kim, Hidewaki Nakagawa, Keunchil Park, Peter J Campbell, Han Liang, null null
Comprehensive molecular characterization of mitochondrial genomes in human cancers. Nature genetics 52 (3) (2020)
Ying Jing, Jin Liu, Youqiong Ye, Lei Pan, Hui Deng, Yushu Wang, Yang Yang, Lixia Diao, Steven Hsesheng Lin, Gordon B Mills, Guanglei Zhuang, Xinying Xue, Leng Han
Multi-omics prediction of immune-related adverse events during checkpoint immunotherapy. Nature communications 11 (1) (2020)
Youqiong Ye, Ying Jing, Liang Li, Gordon B Mills, Lixia Diao, Hong Liu, Leng Han
Sex-associated molecular differences for cancer immunotherapy. Nature communications 11 (1) (2020)
Zhao Zhang, Ji Jing, Youqiong Ye, Zhiao Chen, Ying Jing, Shengli Li, Wei Hong, Hang Ruan, Yaoming Liu, Qingsong Hu, Jun Wang, Wenbo Li, Chunru Lin, Lixia Diao, Yubin Zhou, Leng Han
Characterization of the dual functional effects of heat shock proteins (HSPs) in cancer hallmarks to aid development of HSP inhibitors. Genome medicine 12 (1) (2020)
Yuan Yuan, Young Seok Ju, Young-Wook Kim, Jun Li, Yumeng Wang, Christopher J Yoon, Yang Yang, Inigo Martincorena, Chad J Creighton, John N Weinstein, Yanxun Xu, Leng Han, Hyung-Lae Kim, Hidewaki Nakagawa, Keunchil Park, Peter J Campbell, Han Liang, null null
Author Correction: Comprehensive molecular characterization of mitochondrial genomes in human cancers. Nature genetics (2020)
Kazunari Nohara, Venkata Mallampalli, Travis Nemkov, Marvin Wirianto, Jiah Yang, Youqiong Ye, Yuxiang Sun, Leng Han, Karyn A Esser, Eugenia Mileykovskaya, Angelo D'Alessandro, Carla B Green, Joseph S Takahashi, William Dowhan, Seung-Hee Yoo, Zheng Chen
Nobiletin fortifies mitochondrial respiration in skeletal muscle to promote healthy aging against metabolic challenge. Nature communications 10 (1) (2019)
Shengli Li, Leng Han
Circular RNAs as promising biomarkers in cancer: detection, function, and beyond. Genome medicine 11 (1) (2019)
Hang Ruan, Yingnan Liao, Zongna Ren, Lin Mao, Fang Yao, Peng Yu, Youqiong Ye, Zhao Zhang, Shengli Li, Hanshi Xu, Jiewei Liu, Lixia Diao, Bingying Zhou, Leng Han, Li Wang
Single-cell reconstruction of differentiation trajectory reveals a critical role of ETS1 in human cardiac lineage commitment. BMC biology 17 (1) (2019)
Hang Ruan, Yu Xiang, Junsuk Ko, Shengli Li, Ying Jing, Xiaoyu Zhu, Youqiong Ye, Zhao Zhang, Tingting Mills, Jing Feng, Chun-Jie Liu, Ji Jing, Jin Cao, Bingying Zhou, Li Wang, Yubin Zhou, Chunru Lin, An-Yuan Guo, Xi Chen, Lixia Diao, Wenbo Li, Zhiao Chen, Xianghuo He, Gordon B Mills, Michael R Blackburn, Leng Han
Comprehensive characterization of circular RNAs in ~ 1000 human cancer cell lines. Genome medicine 11 (1) (2019)
Zhao Zhang, Joo-Hyung Lee, Hang Ruan, Youqiong Ye, Joanna Krakowiak, Qingsong Hu, Yu Xiang, Jing Gong, Bingying Zhou, Li Wang, Chunru Lin, Lixia Diao, Gordon B Mills, Wenbo Li, Leng Han
Transcriptional landscape and clinical utility of enhancer RNAs for eRNA-targeted therapy in cancer. Nature communications 10 (1) (2019)
Qingsong Hu, Youqiong Ye, Li-Chuan Chan, Yajuan Li, Ke Liang, Aifu Lin, Sergey D Egranov, Yaohua Zhang, Weiya Xia, Jing Gong, Yinghong Pan, Sujash S Chatterjee, Jun Yao, Kurt W Evans, Tina K Nguyen, Peter K Park, Jiewei Liu, Cristian Coarfa, Sri Ramya Donepudi, Vasanta Putluri, Nagireddy Putluri, Arun Sreekumar, Chandrashekar R Ambati, David H Hawke, Jeffrey R Marks, Preethi H Gunaratne, Abigail S Caudle, Aysegul A Sahin, Gabriel N Hortobagyi, Funda Meric-Bernstam, Lieping Chen, Dihua Yu, Mien-Chie Hung, Michael A Curran, Leng Han, Chunru Lin, Liuqing Yang
Oncogenic lncRNA downregulates cancer cell antigen presentation and intrinsic tumor suppression. Nature immunology 20 (7) (2019)
Youqiong Ye, Qingsong Hu, Hu Chen, Ke Liang, Yuan Yuan, Yu Xiang, Hang Ruan, Zhao Zhang, Anren Song, Huiwen Zhang, Lingxiang Liu, Lixia Diao, Yanyan Lou, Bingying Zhou, Li Wang, Shengtao Zhou, Jianjun Gao, Eric Jonasch, Steven H Lin, Yang Xia, Chunru Lin, Liuqing Yang, Gordon B Mills, Han Liang, Leng Han
Characterization of Hypoxia-associated Molecular Features to Aid Hypoxia-Targeted Therapy. Nature metabolism 1 (4) (2019)
Jixiang Zhang, Peng Tan, Lei Guo, Jing Gong, Jingjing Ma, Jia Li, Minjung Lee, Shaohai Fang, Ji Jing, Gavin Johnson, Deqiang Sun, Wen-Ming Cao, Roderick Dashwood, Leng Han, Yubin Zhou, Wei-Guo Dong, Yun Huang
p53-dependent autophagic degradation of TET2 modulates cancer therapeutic resistance. Oncogene 38 (11) (2018)
Ivan Vannini, Petra M Wise, Kishore B Challagundla, Meropi Plousiou, Mirco Raffini, Erika Bandini, Francesca Fanini, Giorgia Paliaga, Melissa Crawford, Manuela Ferracin, Cristina Ivan, Linda Fabris, Ramana V Davuluri, Zhiyi Guo, Maria Angelica Cortez, Xinna Zhang, Lu Chen, Shuxing Zhang, Cecilia Fernandez-Cymering, Leng Han, Silvia Carloni, Samanta Salvi, Hui Ling, Mariam Murtadha, Paolo Neviani, Barbara J Gitlitz, Ite A Laird-Offringa, Patrick Nana-Sinkam, Massimo Negrini, Han Liang, Dino Amadori, Amelia Cimmino, George A Calin, Muller Fabbri
Publisher Correction: Transcribed ultraconserved region 339 promotes carcinogenesis by modulating tumor suppressor microRNAs. Nature communications 9 (1) (2018)
Peng Tan, Youqiong Ye, Lian He, Jiansheng Xie, Ji Jing, Guolin Ma, Hongming Pan, Leng Han, Weidong Han, Yubin Zhou
TRIM59 promotes breast cancer motility by suppressing p62-selective autophagic degradation of PDCD10. PLoS biology 16 (11) (2018)
Zhao Zhang, Youqiong Ye, Jing Gong, Hang Ruan, Chun-Jie Liu, Yu Xiang, Chunyan Cai, An-Yuan Guo, Jiqiang Ling, Lixia Diao, John N Weinstein, Leng Han
Global analysis of tRNA and translation factor expression reveals a dynamic landscape of translational regulation in human cancers. Communications biology 1 (2018)
Minying Zhang, Jens Fritsche, Jason Roszik, Leila J Williams, Xinxin Peng, Yulun Chiu, Chih-Chiang Tsou, Franziska Hoffgaard, Valentina Goldfinger, Oliver Schoor, Amjad Talukder, Marie A Forget, Cara Haymaker, Chantale Bernatchez, Leng Han, Yiu-Huen Tsang, Kathleen Kong, Xiaoyan Xu, Kenneth L Scott, Harpreet Singh-Jasuja, Greg Lizee, Han Liang, Toni Weinschenk, Gordon B Mills, Patrick Hwu
RNA editing derived epitopes function as cancer antigens to elicit immune responses. Nature communications 9 (1) (2018)
Zhen-Dong Xiao, Leng Han, Hyemin Lee, Li Zhuang, Yilei Zhang, Joelle Baddour, Deepak Nagrath, Christopher G Wood, Jian Gu, Xifeng Wu, Han Liang, Boyi Gan
Energy stress-induced lncRNA FILNC1 represses c-Myc-mediated energy metabolism and inhibits renal tumor development. Nature communications 8 (1) (2017)
Ivan Vannini, Petra M Wise, Kishore B Challagundla, Meropi Plousiou, Mirco Raffini, Erika Bandini, Francesca Fanini, Giorgia Paliaga, Melissa Crawford, Manuela Ferracin, Cristina Ivan, Linda Fabris, Ramana V Davuluri, Zhiyi Guo, Maria Angelica Cortez, Xinna Zhang, Lu Chen, Shuxing Zhang, Cecilia Fernandez-Cymering, Leng Han, Silvia Carloni, Samanta Salvi, Hui Ling, Mariam Murtadha, Paolo Neviani, Barbara J Gitlitz, Ite A Laird-Offringa, Patrick Nana-Sinkam, Massimo Negrini, Han Liang, Dino Amadori, Amelia Cimmino, George A Calin, Muller Fabbri
Transcribed ultraconserved region 339 promotes carcinogenesis by modulating tumor suppressor microRNAs. Nature communications 8 (1) (2017)
Kaiqi Sun, Angelo D'Alessandro, Mostafa H Ahmed, Yujin Zhang, Anren Song, Tzu-Ping Ko, Travis Nemkov, Julie A Reisz, Hongyu Wu, Morayo Adebiyi, Zhangzhe Peng, Jing Gong, Hong Liu, Aji Huang, Yuan Edward Wen, Alexander Q Wen, Vladimir Berka, Mikhail V Bogdanov, Osheiza Abdulmalik, Leng Han, Ah-Lim Tsai, Modupe Idowu, Harinder S Juneja, Rodney E Kellems, William Dowhan, Kirk C Hansen, Martin K Safo, Yang Xia
Structural and Functional Insight of Sphingosine 1-Phosphate-Mediated Pathogenic Metabolic Reprogramming in Sickle Cell Disease. Scientific reports 7 (1) (2017)

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Publication Activity (10 Years)

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Leng Han