Metabolites Produced by an Endophytic Phomopsis sp. and Their Anti-TMV Activity.
Qing-Wei TanPei-Hua FangJian-Cheng NiFangluan GaoQi-Jian ChenPublished in: Molecules (Basel, Switzerland) (2017)
The fermentation and isolation of metabolites produced by an endophytic fungus, which was identified as Phomopsis sp. FJBR-11, based on phylogenetic analysis, led to the identification of six compounds, including dothiorelones A-C, and H, and cytosporones C and U. Among these compounds, cytosporone U exhibited potent inhibitory activity against Tobacco mosaic virus (TMV). Moreover, the crude and a purified exopolysaccharide were proved to possess strong inhibitory effects against the virus infection.