Crenotherapy as a Complementary and Integrative Treatment for Chronic Rhinosinusitis: A Systematic Review and Discussion of Current Evidence Limitations.
Sai V NimmagaddaIsaac L SchmaleLi-Xing ManPublished in: American journal of rhinology & allergy (2022)
There is limited data to support crenotherapy's effectiveness in treating patients with CRS. However, published studies suggest that for certain patients crenotherapy can both improve CRS symptoms and objective measures of nasociliary function with minimal side effects. Findings must be interpreted with caution due to study heterogeneity, inconsistent use of standard CRS definitions and outcomes measures, as well as other study design flaws. Given these results, as well as a growing interest in CIM, crenotherapy treatments for CRS deserve further investigation.
Keyphrases
- end stage renal disease
- chronic rhinosinusitis
- ejection fraction
- newly diagnosed
- chronic kidney disease
- randomized controlled trial
- systematic review
- prognostic factors
- type diabetes
- single cell
- insulin resistance
- adipose tissue
- depressive symptoms
- network analysis
- case control
- meta analyses
- smoking cessation
- replacement therapy