Expression and functional characterization of the large-conductance calcium and voltage-activated potassium channel Kca 1.1 in megakaryocytes and platelets.

Alessandra Balduini Cristiano Fava Christian Andrea Di Buduo Vittorio Abbonante Francesco Massari Alessandra Meneguzzi Paolo M Soprano Francesco TausMarco CastelliAlice Giontella Melania DovizioStefania TacconelliPaola Patrignani Pietro Minuz

Published in: Journal of thrombosis and haemostasis : JTH (2021)

The present study reveals new mechanisms in platelet formation and activation, suggesting that targeting Kca 1.1 channels might be of potential pharmacological interest in hemostasis and thrombosis.

Keyphrases

poor prognosis
pulmonary embolism
drug delivery
climate change
long non coding rna
red blood cell