Assessing Neurofilaments as Biomarkers of Neuroprotection in Progressive Multiple Sclerosis: From the MS-STAT Randomized Controlled Trial.

Thomas E WilliamsKatherine P HoldsworthJennifer M NicholasE Ann YehTheodora KatsanouliHenrietta WellingtonAmanda HeslegraveHenrik ZetterbergChris FrostJeremy Chataway

Published in: Neurology(R) neuroimmunology & neuroinflammation (2022)

This study provides class I evidence that simvastatin treatment does not have a large impact on either serum NfL or NfH, as quantified in this study, in SPMS.

Keyphrases

multiple sclerosis
randomized controlled trial
mass spectrometry
systematic review
ms ms
cerebral ischemia
subarachnoid hemorrhage
replacement therapy