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Assessing Neurofilaments as Biomarkers of Neuroprotection in Progressive Multiple Sclerosis: From the MS-STAT Randomized Controlled Trial.

Thomas E WilliamsKatherine P HoldsworthJennifer M NicholasE Ann YehTheodora KatsanouliHenrietta WellingtonAmanda HeslegraveHenrik ZetterbergChris FrostJeremy Chataway
Published in: Neurology(R) neuroimmunology & neuroinflammation (2022)
This study provides class I evidence that simvastatin treatment does not have a large impact on either serum NfL or NfH, as quantified in this study, in SPMS.
Keyphrases
  • multiple sclerosis
  • randomized controlled trial
  • mass spectrometry
  • systematic review
  • ms ms
  • cerebral ischemia
  • subarachnoid hemorrhage
  • replacement therapy