Conjugated Physiological Resveratrol Metabolites Induce Senescence in Breast Cancer Cells: Role of p53/p21 and p16/Rb Pathways, and ABC Transporters.
Juan Antonio Giménez-BastidaMaría Ángeles Ávila-GálvezJuan Carlos EspínAntonio González-SarríasPublished in: Molecular nutrition & food research (2019)
These data suggest that RSV metabolites, as found in MT from BC patients, are not de-conjugated to release free RSV, but enter the cells and may exert long-term tumor-senescent chemoprevention.
Keyphrases
- breast cancer cells
- end stage renal disease
- ms ms
- newly diagnosed
- ejection fraction
- photodynamic therapy
- induced apoptosis
- chronic kidney disease
- respiratory syncytial virus
- prognostic factors
- respiratory tract
- cell cycle arrest
- endothelial cells
- dna damage
- patient reported outcomes
- cell death
- artificial intelligence