Pleiotropic Effects of a KCNQ1 Variant on Lipid Profiles and Type 2 Diabetes: A Family-Based Study in China.
Xiaowen WangJunhui WuYao WuMengying WangZijing WangTao WuDafang ChenXun TangXueying QinYi-Qun WuYong-Hua HuPublished in: Journal of diabetes research (2020)
KCNQ1 had pleiotropic effects on lipids and T2DM, and the unexpected genetic effect on association of HDL-C with T2DM was observed, indicating the different pathways to lipids and T2DM. Further research studies are needed to verify potential biological mechanisms.