Effects of N-acetyl cysteine on mitochondrial ROS, mitochondrial dynamics, and inflammation on lipopolysaccharide-treated human apical papilla cells.
Nutcha JariyamanaPatchanee ChuveeraAnat DewiWarat LeelapornpisidJitjiroj IttichaicharoenSiriporn ChattipakornTanida SrisuwanPublished in: Clinical oral investigations (2021)
Ten-minute NAC application is sufficient to reduce the level of inflammation and maintain the mitochondrial dynamics. Therefore, NAC may be considered as a potential adjunctive irrigation solution in REPs.
Keyphrases
- oxidative stress
- induced apoptosis
- transcription factor
- dna damage
- endothelial cells
- inflammatory response
- cell death
- cell cycle arrest
- toll like receptor
- induced pluripotent stem cells
- reactive oxygen species
- endoplasmic reticulum stress
- lps induced
- immune response
- genome wide analysis
- pluripotent stem cells
- living cells