Test-retest reliability and sensitivity to change of ultrasound-based methods of measuring synovial inflammation in knee osteoarthritis.

Holly T Philpott Trevor B BirminghamRobert DimaRyan PintoDianne BryantChristopher Thomas Appleton

Published in: Arthritis care & research (2022)

In a clinical setting, US measures of inflammatory features of knee OA demonstrated substantial reliability and low-to-moderate sensitivity to change, whereas measures of structural OA features were less reliable. Longitudinal construct validity of US measures of synovitis and effusion to KOOS pain was not strongly supported.

Keyphrases

knee osteoarthritis
oxidative stress
chronic pain
magnetic resonance imaging
pain management
neuropathic pain
high intensity
cross sectional
total knee arthroplasty
computed tomography
spinal cord injury