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Long-term treatment effects of inotersen on health-related quality of life in patients with hATTR amyloidosis with polyneuropathy: Analysis of the open-label extension of the NEURO-TTR trial.

Chafic KaramDuncan BrownMin YangNicolae DoneJing Jing ZhuAlexandra GreatsingerAna BozasMontserrat Vera-LlonchJames Signorovitch
Published in: Muscle & nerve (2022)
Long-term (>3 years) inotersen treatment was associated with slowing and, in some domains, halting of deterioration in key HRQL outcome measures, particularly physical functioning and pain.
Keyphrases
  • open label
  • physical activity
  • mental health
  • phase iii
  • chronic pain
  • randomized controlled trial
  • pain management
  • spinal cord injury
  • multiple myeloma
  • spinal cord
  • replacement therapy
  • smoking cessation