Benznidazole treatment decreases IL-6 levels in Trypanosoma cruzi-infected human adipocytes differentiated from adipose tissue-derived stem cells.
Leyllane Rafael MoreiraAna Carla SilvaCíntia Nascimento da Costa OliveiraClaudeir Dias da Silva JúniorAmanda Vasconcelos NascimentoKamila Kássia Dos Santos OliveiraAna Karine de Araújo SoaresKarina Lidianne Alcântara SaraivaMilena de Paiva CavalcantiVirginia Maria Barros de LorenaPublished in: Memorias do Instituto Oswaldo Cruz (2023)
Therefore, we believe that BZ has a beneficial role as it reduces inflammation in infected fat cells.
Keyphrases
- trypanosoma cruzi
- adipose tissue
- stem cells
- induced apoptosis
- endothelial cells
- insulin resistance
- oxidative stress
- high fat diet
- cell cycle arrest
- induced pluripotent stem cells
- endoplasmic reticulum stress
- pluripotent stem cells
- cell death
- cell therapy
- signaling pathway
- combination therapy
- metabolic syndrome
- cell proliferation
- replacement therapy
- pi k akt