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An in vitro dynamic bioreactor model for evaluating antimicrobial effectiveness on periodontal polymicrobial biofilms: a proof-of-concept study.

Srinivas Sulugodu RamachandraFekade Bruck SimeSaiyuri NaickerPingping HanRyan S B LeeSteven C WallisJason Alexander RobertsSašo Ivanovski
Published in: Journal of periodontology (2023)
A novel in vitro dynamic model of oral microcosm biofilms was effective in modeling the antimicrobial effect of a pharmacokinetically simulated clinically relevant dose of amoxicillin.
Keyphrases
  • staphylococcus aureus
  • candida albicans
  • randomized controlled trial
  • systematic review