Corpus callosal lipoma is a rare and unrecognised cause of secondary headache. It should be suspected in patients with atypical headache without papilledema and unresponsive to analgesics. This may be the only presenting feature of intracranial lipomas rendering it even more difficult to suspect and diagnose, thus emphasizing the importance of evaluating secondary headaches. Diagnosis is important because long term follow-up may be required if patients develop new focal deficits, which may necessitate surgical intervention.