Muscle hypertrophy training does not suppress the GH/IGF axis in young adult males.

Marcos Corrêa JuniorH S C CerqueiraH T FilhoC E M Junior

Published in: Journal of endocrinological investigation (2023)

The resistance training protocol prescribed for muscle hypertrophy did not suppress the GH-IGF-I axis, but it did cause alterations in IGF-1r gene expression and in IGF-I kinetics compatible with increased IGF bioactivity.

Keyphrases

growth hormone
resistance training
gene expression
pi k akt
binding protein
young adults
skeletal muscle
body composition
randomized controlled trial
dna methylation
high intensity
signaling pathway
cell proliferation