Ambient air pollution sensitivity and severity of pediatric asthma.
Jelte KelchtermansFrank MentchHakon HakonarsonPublished in: Journal of exposure science & environmental epidemiology (2023)
There is a subpopulation of pediatric asthma patients that experience asthma exacerbations just following spikes in ambient air pollution. This subgroup of patients has more severe asthma despite correction for significant confounders. The presented work is the first to reveal the clinically significant impact of variation in ambient air pollution sensitivity in pediatric asthma, highlighting the importance of accounting for variable sensitivity in the study of the effects of ambient air pollution exposure on pediatric asthma.
Keyphrases
- air pollution
- lung function
- particulate matter
- chronic obstructive pulmonary disease
- end stage renal disease
- ejection fraction
- newly diagnosed
- allergic rhinitis
- chronic kidney disease
- cystic fibrosis
- prognostic factors
- peritoneal dialysis
- randomized controlled trial
- young adults
- patient reported outcomes
- dna methylation