A single bout of resistance exercise triggers mitophagy, potentially involving the ejection of mitochondria in human skeletal muscle.
Francisco Díaz-CastroMauro Tuñón-SuárezPatricia RiveraJavier BotellaJorge CancinoAna María FigueroaJuan GutiérrezClaudette CantinLouise DeldicqueHermann Zbinden-FonceaJoachim NielsenCarlos Henríquez-OlguínEugenia MorselliMauricio A Castro-SepulvedaPublished in: Acta physiologica (Oxford, England) (2024)
The findings suggest that a single bout of resistance exercise can initiate mitophagy, potentially involving mitochondrial ejection, in human skeletal muscle. BNIP3L/NIX is proposed as a sensitive marker for assessing mitophagy flux in SkM.